Scripps NeuroAIDS Preclinical Studies (SNAPS)

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2004 2003 2002 2000-2001

Scripps NeuroAIDS Preclinical Studies (SNAPS) Center
Supported by the National Institute for Mental Health
P30 MH62261
Publications 2000-2001

  1. Asensio, V.C., J. Maier, R. Milner, K. Boztug, C. Kincaid, M. Moulard, C. Phillipson, K. Lindsley, T. Krucker, H.S. Fox, and I.L. Campbell, Interferon-independent, human immunodeficiency virus type 1 gp120-mediated induction of CXCL10/IP-10 gene expression by astrocytes in vivo and in vitro. J Virol, 2001. 75:7067-77.
  2. Barr, M.C., J.N. Billaud, D.R. Selway, S. Huitron-Resendiz, K.G. Osborn, S.J. Henriksen, and T.R. Phillips, Effects of multiple acute morphine exposures on feline immunodeficiency virus disease progression. J Infect Dis, 2000. 182:725-32.
  3. Barr, M.C., S. Huitron-Resendiz, D.R. Selway, S.J. Henriksen, and T.R. Phillips, Exogenous glucocorticoids alter parameters of early feline immunodeficiency virus infection. J Infect Dis, 2000. 181:576-86.
  4. Beck, Z.Q., Y.C. Lin, and J.H. Elder, Molecular basis for the relative substrate specificity of human immunodeficiency virus type 1 and feline immunodeficiency virus proteases. J Virol, 2001. 75:9458-69.
  5. Flodstrom, M., M.S. Horwitz, A. Maday, D. Balakrishna, E. Rodriguez, and N. Sarvetnick, A critical role for inducible nitric oxide synthase in host survival following coxsackievirus B4 infection. Virology, 2001. 281:205-15.
  6. Fox, H.S., M.R. Weed, S. Huitron-Resendiz, J. Baig, T.F. Horn, P.J. Dailey, N. Bischofberger, and S.J. Henriksen, Antiviral treatment normalizes neurophysiological but not movement abnormalities in simian immunodeficiency virus-infected monkeys. J Clin Invest, 2000. 106:37-45.
  7. Giralt, M., J. Carrasco, M. Penkowa, M.A. Morcillo, J. Santamaria, I.L. Campbell, and J. Hidalgo, Astrocyte-targeted expression of interleukin-3 and interferon-alpha causes region-specific changes in metallothionein expression in the brain. Exp Neurol, 2001. 168:334-46.
  8. Kakimi, K., T.E. Lane, S. Wieland, V.C. Asensio, I.L. Campbell, F.V. Chisari, and L.G. Guidotti, Blocking chemokine responsive to gamma-2/interferon (IFN)-gamma inducible protein and monokine induced by IFN-gamma activity in vivo reduces the pathogenetic but not the antiviral potential of hepatitis B virus-specific cytotoxic T lymphocytes. J Exp Med, 2001. 194:1755-66.
  9. King, C., R. Mueller Hoenger, M. Malo Cleary, K. Murali-Krishna, R. Ahmed, E. King, and N. Sarvetnick, Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter-regulate cytotoxic CD8+ T-cell responses. Nat Med, 2001. 7:206-14.
  10. Lassmann, S., C. Kincaid, V.C. Asensio, and I.L. Campbell, Induction of type 1 immune pathology in the brain following immunization without central nervous system autoantigen in transgenic mice with astrocyte-targeted expression of IL-12. J Immunol, 2001. 167:5485-93.
  11. Marcondes, M.C., E.M. Burudi, S. Huitron-Resendiz, M. Sanchez-Alavez, D. Watry, M. Zandonatti, S.J. Henriksen, and H.S. Fox, Highly activated CD8(+) T cells in the brain correlate with early central nervous system dysfunction in simian immunodeficiency virus infection. J Immunol, 2001. 167:5429-38.
  12. Marinzi, C., S.J. Bark, J. Offer, and P.E. Dawson, A new scaffold for amide ligation. Bioorg Med Chem, 2001. 9:2323-8.
  13. McGuire, M.V., P. Suthipinijtham, and N.R. Gascoigne, The mouse Supt16h/Fact140 gene, encoding part of the FACT chromatin transcription complex, maps close to Tcra and is highly expressed in thymus. Mamm Genome, 2001. 12:664-7.
  14. O'Barr, S.A., J. Caguioa, D. Gruol, G. Perkins, J.A. Ember, T. Hugli, and N.R. Cooper, Neuronal expression of a functional receptor for the C5a complement activation fragment. J Immunol, 2001. 166:4154-62.
  15. Phillips, T.R., J.N. Billaud, and S.J. Henriksen, Methamphetamine and HIV-1: potential interactions and the use of the FIV/cat model. J Psychopharmacol, 2000. 14:244-50.
  16. Sanchez-Alavez, M., J. Criado, M. Gomez-Chavarin, A. Jimenez-Anguiano, L. Navarro, O. Diaz-Ruiz, O. Galicia, F. Sanchez-Narvaez, E. Murillo-Rodriguez, S.J. Henriksen, J.H. Elder, and O. Prospero-Garcia, HIV- and FIV-derived gp120 alter spatial memory, LTP, and sleep in rats. Neurobiol Dis, 2000. 7:384-94.
  17. Saphire, E.O., P.W. Parren, R. Pantophlet, M.B. Zwick, G.M. Morris, P.M. Rudd, R.A. Dwek, R.L. Stanfield, D.R. Burton, and I.A. Wilson, Crystal structure of a neutralizing human IGG against HIV-1: a template for vaccine design. Science, 2001. 293:1155-9.
  18. Shi, F.D., M. Flodstrom, B. Balasa, S.H. Kim, K. Van Gunst, J.L. Strominger, S.B. Wilson, and N. Sarvetnick, Germ line deletion of the CD1 locus exacerbates diabetes in the NOD mouse. Proc Natl Acad Sci U S A, 2001. 98:6777-82.
  19. Shi, F.D., K. Takeda, S. Akira, N. Sarvetnick, and H.G. Ljunggren, IL-18 directs autoreactive T cells and promotes autodestruction in the central nervous system via induction of IFN-gamma by NK cells. J Immunol, 2000. 165:3099-104.
  20. Swartz, K.R., F. Liu, D. Sewell, T. Schochet, I. Campbell, M. Sandor, and Z. Fabry, Interleukin-6 promotes post-traumatic healing in the central nervous system. Brain Res, 2001. 896:86-95.