Friday Evening, October 15

 
3:00 PM Check-in, Asilomar Main Lobby
6:00-7:00 PM Asilomar dinner. Crocker Dinging Hall. Meal ticket required.
6:30 PM Speakers, please connect laptops if using LCD projection, Chapel
6:30 PM Posters: Please set up 1-9 (see page 5), Chapel
7:00-10:00 PM OPENING SESSION. Chapel
7:00-7:10 PM Gary Siuzdak, The Scripps Research Institute Introductory Remarks
7:15-7:55 PM Donald Chace, Pediatrix Newborn Screening for Metabolic Disease is one Model for the Practice of Clinical Mass Spectrometry
8:00-8:40 PM Xianlin Han, Washington University School of Medicines Shotgun Lipidomics and Application for Biomarker Discovery in Alzheimer’s Disease
8:45 PM POSTER PRESENTATIONS, 5 minutes each
  S.J. Robinson, Department of Chemistry, University of York Mass Spectrometric Approaches to Carbohydrate Metabolomics in Wheat
  Thomas O. Metz, Battelle Laboratories Application of the Accurate Mass and Time (AMT) Tag Approach to Global Metabolomics Studies of Microbial Systems
  Grace Tong, The Scripps Research Institute Chemical Derivatization and Data Analysis Approaches to Metabolite Profiling
  Brian Frey, Department of Chemistry, University of Wisconsin—Madison Metabolic Profiling of Pancreatic Islets and a Novel Ionization Method for Mass Spectrometric Analysis of Metabolite Mixtures
9:15-10:00 PM Poster Viewing and Reception. Chapel

Saturday Morning, October 16

 
7:30-9:00 AM Asilomar breakfast. Crocker Dining Hall. Meal ticket required.
8:30-9:00 AM Speakers, please connect laptops if using LCD projection. Chapel
9:00-12:00 PM Endogenous Metabolites and Xenobiotics
9:00-9:30 AM John A. Wagner, Department of Clinical Pharmacology, Merck Research Laboratories Biomarkers in Rational Drug Development
9:30-10:00 AM John Vogel, Center for Accelerator Mass Spectrometry, University of California/Lawrence Livermore National Laboratory AMS Quantitation of Metabolism: From Individual Humans to Individual Cells
10:00-10:30 AM Alan Saghatelian, The Scripps Research Institute Assigning Endogenous Substrates of Enzymes by Global Metabolite Profiling
10:30-10:45 AM BREAK
10:45-11:15 AM William Griffiths, University of London Targeted Metabolomics: Novel Cholesterol Metabolites in Brain
11:15-11:45 AM C. Logan Mackay, National High Magnetic Field Laboratory, Florida State University Capillary Electrophoresis and Top Down ESI FT-ICR Mass Spectrometry for the Characterization of Renal Disease Biomarkers.
12:00-2:00 PM Asilomar lunch. Crocker Dining Hall. Meal ticket required.

Saturday Afternoon, October 16

 
1:30-2:00 PM Speakers, please connect laptops if using LCD projection. Chapel
2:00-6:00 PM Metabolite Bioinformatics
2:00-2:30 PM Colin Smith, The Scripps Research Institute METLIN: A Metabolite Profiling Database
2:30-3:00 PM Robert Mistrik, HighChem, Ltd. Mapping the Human Metabolome: A software problem?
3:00-3:30 PM Thomas Hankemeijer, TNO/ Leiden University Metabolomics: Quo vadis?
3:45-4:00 PM BREAK
4:00 PM POSTER PRESENTATIONS, 5 minutes each
  Paul E. Minkler, Louis Stokes VA Medical Center Determination of Carnitine and Acylcarnitines in Biological Matrices by HPLC/ESI/MS
  Emma Edwards, Department of Chemistry, University of York LC-MS and CE-MS Approaches for the Analysis of Biologically Generated Pharmaceutical Metabolites
  Darren S. Dumlao, Chemistry & Biochemistry Department, UCLA Methyltransferome to Metabolites: The use of Metabolomics in the Identification of the Major Substrate (3-isopropylmalate) for a known Saccharomyces Cerevisiae Enzyme (Tras-Aconitate Methyltransferase)
  Michael Zhou, Cardinal Health Pharmaceutical/Biopharmaceutical Development Applications of Automated HTLC-MS/MS in Bioanalytical/Biotech Laboratories
  Zhihong Z. O’Brien, Ligand Pharmaceutical Inc. Perillyl Alcohol, A Model Substrate for Multiple Phase I and Phase II Metabolic Profiling
  Lekha Sleno, National Research Council MALDI triple quadrupole MS for Small Molecule Quantitation and Screening in Biological Samples
5:30 PM Remove posters 1-9. Set posters 10-17. See page 6.
6:00-7:00 PM Asilomar dinner. Crocker Dining Hall. Meal ticket required.
7:00-10:00 PM Informal Gathering. Surf & Sand Living Room

Sunday Morning, October 17

 
7:30-9:00 AM Asilomar breakfast. Crocker Dining Hall. Meal ticket required.
8:30-9:00 AM Speakers, please connect laptops if using LCD projection. Chapel
9:00-1200 PM Separation Technology
9:00-9:30 AM Richard D. Smith, Battelle Laboratories Nanoflow Capillary Liquid Chromatographic-Mass Spectrometry for High Throughput Quantitative Metabolomic Analyses
9:30-10:00 AM Andrew Baker, Waters Corp. UPLC-MS for increased throughput, sensitivity and resolution
10:00-10:30 AM Ben Bolanos, Pfizer Leveraging SFC/MS to Broaden Plasma Biomarker Metabolite Profiling
10:30-10:45 BREAK - Profiling
10:45-11:15 AM Elizabeth Want, The Scripps Research Institute Metabolite Profiling in Disease
11:15-11:45 AM David S. Millington, Duke University Medical Center Applications of Targeted Metabolic Profiling
12:00-1:00 PM Asilomar lunch. Crocker Dining Hall. Meal ticket required.

Sunday Evening, October 17

 
6:00-7:00 PM Asilomar dinner. Crocker Dining Hall. Meal ticket required.
7:00-8:30 PM Global Systems Biology and the Human Superorganism
7:00-7:40 PM Jeremy Nicholson, Imperial College Understanding Global Systems Biology and the Human Superorganism: The Greatest Challenge in Analytical Chemistry and 21st Century Medicine?
7:45-8:30 PM POSTER PRESENTATIONS, 5 minutes each
  Charles L. Hoppel, Louis Stokes VA Medical Center Isolation and Identification of Two Forms of Malonyl-CoA in Commercial Malonyl-CoA
  Qingfen Zhang, Chemistry Department, The University of Arizona Ammonia Metabolism in Mosquitoes Examined by Mass Spectrometry in Multiple-reaction Monitoring Mode
  Ming Gu, Cerno Bioscience A Novel Approach to Achieve High Mass Accuracy for LC/MS Metabolite Identification
  Arman Yaghoubian, The Pasarow Mass Spectrometry Laboratory, UCLA Measurement of Urinary Psychosine using ESI-MS2
8:30-10:00 PM Informal Gathering. Surf & Sand Living Room

Monday Morning, October 18

 
7:30-9:00 AM Asilomar breakfast. Crocker Dining Hall. Meal ticket required.
8:30-9:00 AM Speakers, please connect your laptops if using LCD projection. Chapel
9:00-12:00 PM Technology Developmets
9:00-9:30 AM Jack Henion, Cornell University/ Advion Biosciences Chip-Based NanoElectrospray Screening of Biological Samples for Disease Biomarkers
9:30-10:00 AM James Kapron, Ionalytics Corp. Targeted Bioanalysis with LC-FAIMS-MS (and MS/MS)
10:00-10:30 AM Carsten Baessmann, Bruker Daltonik, Gmbh Metabolic Profiling and Characterization of potential Biomarkers in Biological Fluids using LC-MS-NMR
10:30-10:45 AM BREAK
10:45-11:15 AM Joseph Dalluge, Cargill, Inc. Discovery of Novel Enzymatic Activity Using Stable Isotope Metabolite Labeling and LC/MS
11:15-11:45 AM Jennifer Granger, Waters Corp. A Metabonomics Time Course Analysis of Zucker Rat Urine using UPLC-MS(TOF)
12:00-2:00 PM Asilomar lunch. Crocker Dining Hall. Meal tickets required.

Monday Afternoon, October 18

 
1:30-2:00 PM Speakers, please connect your laptops if using LCD projection. Chapel
2:00-2:30 PM Technology
2:00-2:30 PM Marlin Friesen, International Agency for Research on Cancer, France and National Cancer Institute Measurement of Metabolite Induced Ser-249 TP53 Mutation by Short Oligonucleotide Mass Analysis (SOMA): A Mass Spectrometric Approach to Mutation Analysis
2:30-3:00 PM Laszlo Boros, SIBDMAP and Harbor-UCLA Medical Center Metabolic profiling using stable isotope tracer technology GC/MS
3:00-3:30 PM Mark O'Neil-Johnson, Sequoia Sciences Accelerated Structure Elucidation Using FT/MS and CapNMR Spectroscopy
3:30-6:00 PM POSTER VIEWING
6:30 PM BANQUET for all registrants and registered guests, Seascape in Crocker Dining Hall, ticket required.

Tuesday Morning, October 19

 
7:30-9:00 AM Asilomar breakfast. Crocker Dining Hall. Meal ticket required.
12:00-1:00 PM Asilomar lunch. Crocker Dining Hall. Meal ticket required.
 
Please complete the evaluation form on page 14 prior to departing. Thank you.
 

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